I'm just stating the obvious, but whatever is in store for the RX 330
is likely in store for the 400h. I do not know what may be in store
for either, but you'll probably have an easier time researching changes
in the 330.
Since the RX body style was just changed in 2004, it probably won't be
for a while. Lexus still has a few other body styles to update before
they circle back to the RX.
Would the new generation RX or Hybrid RX eventually become the Lexus
HPX? You can see some photos in the internet on Lexus HPX. Perhaps go
and type the search engine on images for "Lexus HPX". I saw the ones
with grey colour, with camera side mirrors, very smart looking, but
closer to a station wagon...